Synthetic and Medicinal Chemistry
Associate Professor: Hiroki Kakuta
Most therapeutic agents in clinical use today are small molecules. Compared to newer antibody drugs, oligonucleotide therapeutics, etc., they are generally easier to produce, less expensive, and more compatible with the Sustainable Development Goals (SDGs) set by the United Nations in 2015. We believe such small-molecule drugs can serve as “activators of potential self-healing ability”. We aim to produce new drug candidates, focusing on not only synthetic organic chemistry, but also evaluation of drug efficacy, dynamics, and toxicity.
Keywords
drug discovery, small molecules, organic chemistry, autoimmune diseases, lipid and glucose metabolism, inflammation, nuclear receptors, RXR, retinoids, inflammatory bowel disease, BNCT, PET imaging
Site
http://www.cc.okayama-u.ac.jp/~kakuta-h/kakuta_lab/index.html
Contact
Professor:KAKUTA Hiroki
E-mail:kakuta-h
okayama-u.ac.jp