{"id":192,"date":"2021-12-08T14:28:28","date_gmt":"2021-12-08T05:28:28","guid":{"rendered":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/?page_id=192"},"modified":"2025-03-10T09:55:22","modified_gmt":"2025-03-10T00:55:22","slug":"structural-biology","status":"publish","type":"page","link":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/about\/professors\/structural-biology\/","title":{"rendered":"Structural Biology"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-193 aligncenter\" src=\"http:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-content\/uploads\/sites\/2\/2021\/12\/y_20_m.png\" alt=\"\" width=\"1200\" height=\"450\" srcset=\"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-content\/uploads\/sites\/2\/2021\/12\/y_20_m.png 1200w, https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-content\/uploads\/sites\/2\/2021\/12\/y_20_m-300x113.png 300w, https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-content\/uploads\/sites\/2\/2021\/12\/y_20_m-1024x384.png 1024w, https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-content\/uploads\/sites\/2\/2021\/12\/y_20_m-768x288.png 768w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><\/p>\n<h2>Professor: Undecided<\/h2>\n<p>We address the mechanism of sensing by structural and functional analyses of sensory receptors, such as taste receptors, and relating proteins. We also proceed with structural and functional studies on membrane proteins and signal transduction proteins that are targets for drug discovery. Simultaneously, we develop methodologies to promote sample preparation and functional analysis, which are bottlenecks in these analyses. Furthermore, we design and generate &#8220;synthetic binding proteins&#8221; that are used in various researches including the above issues.<\/p>\n<h3>Keywords<\/h3>\n<p>taste, X-ray crystallography, intermolecular interaction, synthetic binding protein, directed evolution<\/p>\n<h3>Site<\/h3>\n<p><a href=\"https:\/\/www.pharm.okayama-u.ac.jp\/lab\/a_yama\/Structure\/Top.html\" target=\"_blank\" rel=\"noopener\">https:\/\/www.pharm.okayama-u.ac.jp\/lab\/a_yama\/Structure\/Top.html<\/a><\/p>\n<h3>Contact<\/h3>\n<p>Associate Professor:YASUI Norihisa<br \/>\nE-mail:nyasui<img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-42 alignnone\" src=\"http:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-content\/uploads\/sites\/2\/2021\/12\/at.png\" alt=\"\" width=\"15\" height=\"18\">okayama-u.ac.jp<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor: Undecided We address the mechanism of sensing by structural and functional analyses of sensory rece [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":55,"menu_order":43,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-192","page","type-page","status-publish","hentry"],"aioseo_notices":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-28 06:46:56","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/192","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/comments?post=192"}],"version-history":[{"count":2,"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/192\/revisions"}],"predecessor-version":[{"id":4442,"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/192\/revisions\/4442"}],"up":[{"embeddable":true,"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/55"}],"wp:attachment":[{"href":"https:\/\/www.mdps.okayama-u.ac.jp\/en\/wp-json\/wp\/v2\/media?parent=192"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}